Introduction Are you tired of hearing about the latest weight loss supplement that promises to be the next big thing? Well, I am too. Recently, I was asked to comment on berberine, a dietary supplement called that has been gaining momentum on social media for its potential weight loss benefits. Some people are even calling it "nature's Ozempic," comparing it to the popular prescription medication used to treat diabetes and support weight management. But is berberine really a natural replacement for GLP-1 agonists like Ozempic and Wegovy? Fortunately, I am very familiar with berberine. I've been taking the supplement since 2020 after conducting extensive literature search. As the buzz around berberine grows, I want to separate facts from fiction. While some studies suggest that berberine may offer weight loss and blood sugar control benefits, it's crucial to understand that we are comparing apples to oranges when we are comparing berberine to prescription medications like semaglutide (the active ingredient in Ozempic and Wegovy) or tirzepatide (Mounjaro and Zepbound). In this blog post, I will discuss berberine, its potential benefits and risks, and how it compares to GLP-1 agonists. I'll also discuss what you should know before considering berberine for weight loss. By the end of this article, you'll have a clearer understanding of whether berberine is truly "nature's Ozempic" or just another overhyped supplement. What is Berberine? Berberine is a natural compound found in several plants, including goldenseal, Oregon grape, and barberry. It's been used for centuries in traditional Chinese and Ayurvedic medicine to treat various ailments, such as digestive issues, infections, and inflammation. In recent years, berberine has gained attention for its potential to help people with type 2 diabetes manage blood sugar levels and support weight loss. I first heard of berberine through the Peter Attia podcast, the drive, and he made a compelling argument that encouraged me to do further research. I was happy with what I read and began using it for a specific purpose. As a dietary supplement, berberine is usually taken in capsule form. It's believed to work by activating an enzyme called AMP-activated protein kinase (AMPK), which plays a role in regulating metabolism.  AMPK is found in all mammalian cells. When AMPK is activated, it may help the body burn fat more efficiently and improve insulin sensitivity, which can lead to better blood sugar control. Some studies have also suggested that berberine may inhibit the absorption of carbohydrates in the gut, further contributing to its potential benefits for people with diabetes or those looking to lose weight. While the exact mechanisms behind berberine's effects are still being researched, some studies have shown promising results. For example, a review of 27 randomized controlled trials found that taking berberine daily, at doses of 500 mg to 1,500 mg per day, can lower blood sugar levels and improve markers of diabetes management. However, it's important to note that most of these studies were small and short-term, so more research is needed to fully understand berberine's long-term effects and safety. How Does Berberine Compare to Ozempic, Wegovy, Tirzepatide, Mounjaro and Zepbound? Now you've come to the "meat" of the article. Ozempic and Wegovy (semaglutide), Mounjaro (tirzepatide), and Zepbound (a combination of semaglutide and tirzepatide) are all prescription medications that belong to a class of drugs called GLP-1 receptor agonists. These medications work by mimicking the effects of hormones called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are naturally produced in the gut. When GLP-1 and GIP levels are high, they can help the body feel fuller, reduce appetite, and slow down digestion, leading to reduced food intake and, ultimately, help you lose weight. Think of GLP and GIP as the off switch when feeding. Semaglutide and tirzepatide take this natural process a step further by binding to GLP-1 and GIP receptors and stimulating them for longer periods, turning off hunger for longer periods and thus causing significant weight loss. In clinical trials, people taking Ozempic or Wegovy lost an average of 15% to 20% of their body weight over 68 weeks, while those taking Mounjaro (tirzepatide) or Zepbound (tirzepatide) lost an average of 22.5% of their body weight over 72 weeks. On the other hand, berberine works differently than these GLP-1 and GIP receptor agonists. While it may help with modest weight loss by activating AMPK and improving insulin sensitivity, it doesn't directly target GLP-1 or GIP receptors like semaglutide and tirzepatide do. This means that the weight loss effects of berberine are not even close to those of Ozempic, Wegovy, Mounjaro, or Zepbound. While semaglutide and tirzepatide have been extensively studied in large, long-term clinical trials and have been approved by the Food and Drug Administration (FDA) for treating obesity, the evidence for berberine's weight loss effects is slim, no pun intended. Most studies on berberine and weight loss have been small, short-term, and have shown small results, with participants losing an average of 3 to 5 pounds over 12 to 16 weeks. Does Berberine Work for Weight Loss? From an anecdotal perspective, I've seen berberine work to lower blood glucose and weight in my patients. However, when making claims that it's 'nature's Ozempic' it's important to look at the evidence critically. A 2020 review of 11 randomized controlled trials found that berberine supplementation led to an average weight loss of 3.5 pounds (1.6 kg) compared to placebo over 12 to 16 weeks. This is a minuscule amount of weight loss, especially when compared to the results seen with prescription weight loss drugs like Ozempic, Wegovy, and Mounjaro. But the studies in this review had small sample sizes and short durations, making it difficult to draw firm conclusions about berberine's long-term effectiveness and safety for weight loss. Also, the dosages of berberine used in these studies varied widely, ranging from 500 mg to 1,500 mg per day, which makes it challenging to determine the optimal dose for weight loss. Is Berberine Safe to Take? In terms of safety, berberine is generally well-tolerated when taken at recommended doses. But I remind you that whether a substance is natural or not, if it has an effect, it has a side effect. Common side effects of berberine include digestive issues, headaches, and constipation in some people. Berberine may also interact with certain medications, including antibiotics, diabetes drugs, and blood pressure medications, so it's crucial to talk to your doctor before taking berberine, especially if you have any underlying health conditions or are taking any medications. As a dietary supplement, berberine is not as closely regulated as prescription drugs. This means that the quality, purity, and potency of berberine supplements can vary widely between brands, making it difficult to ensure that you're getting a safe and effective product. What You Should Know Before Trying Berberine for Weight Loss Before considering berberine for weight loss, it's essential to consult your healthcare provider, especially if you have any underlying health conditions or are taking medications. Your doctor can help you determine whether berberine is safe and appropriate for you and can monitor your progress and any potential side effects. You have to set realistic expectations about the potential weight loss benefits of berberine. While some studies have shown minor results, berberine is not a magic solution for rapid weight loss. Sustainable weight loss requires a comprehensive approach that includes a healthy diet, regular exercise, and other lifestyle changes. Berberine should be seen as a potential complement to these efforts, not a replacement for them. When choosing a berberine supplement, look for products that have been independently tested and certified by third-party organizations like USP or NSF International to ensure quality and purity. Remember that berberine is not as well-studied or potent as prescription medications like Ozempic, Wegovy, Mounjaro, and Zepbound. These GLP-1 and GIP receptor agonists are the greatest inventions yet in the battle to manage weight. If you're struggling with obesity or significant weight gain, it's worth discussing these prescription options with your doctor rather than relying solely on supplements like berberine. The Final Verdict - Is Berberine Nature's Ozempic? In my professional opinion, berberine is not even close to Ozempic. The idea of berberine as "nature's Ozempic" is a misleading and potentially dangerous claim. While berberine may offer some benefits for blood sugar control and weight management, it simply cannot match the proven efficacy and safety of prescription GLP-1 and GIP receptor agonists like Ozempic, Wegovy, Mounjaro, and Zepbound. The extensive clinical trials behind these medications have shown remarkable weight loss results, with participants losing up to 20% or more of their body weight. In contrast, the limited studies on berberine have only demonstrated modest weight loss of a few pounds over several weeks or months. Moreover, relying on unregulated supplements like berberine for significant weight loss can be risky, as the quality and purity of these products can vary widely. It's crucial to prioritize your health and well-being by working closely with your healthcare provider to develop a safe and effective weight loss plan that may include proven medications and lifestyle changes. Don't fall for the hype surrounding berberine as a natural weight loss solution. Trust in the science and evidence behind prescription GLP-1 and GIP receptor agonists, and consult your doctor to determine the best approach for your individual needs. Remember, when it comes to significant weight loss and management, there's no substitute for proven medications and a comprehensive, medically-supervised approach. Disclaimer: This blog post is for the educational purpose of my current patients who are in a Medication Assisted Treatment under my care. For all others, this blog post is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your doctor or other qualified health provider with any questions you may have regarding your health, a medical condition, or anything you've learned from this article and let them decide if this information is right for you.

Introduction Struggling with obesity is frustrating. Losing weight through eating less and exercising more takes lots of effort. And most people end up regaining the pounds later on. So it feels like you can’t win. That’s why the only option that seems to work long-term is surgery – like gastric bypass or gastric sleeve procedures. But who wants their stomach stapled or guts re-routed if there was an alternative? To make matters worse, people gain weight after surgery. Well, new medications that target appetite signals in the brain could finally offer that alternative. And we’re not talking about taking a pill to lose 5 pounds. We’re talking about pounds melting off to the tune of over 20% of your body weight or more! How is that possible without surgery? Well, obesity doesn’t happen because of a lack of willpower. It’s a disease influenced by issues in appetite regulation. See, your gut sends signals to your brain affecting how hungry you feel and how many calories you burn. The Appetite Control System For example, hormone signals like GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) make you feel fuller. Others like glucagon rev up your metabolism. New breakthrough drugs called “combination therapies” bind to multiple appetite targets at once. Almost like a key fitting in different locks. The most exciting ones? Tirzepatide, targeting GLP-1 and GIP, leads to 22% weight loss. And Retatrutide, tripling down on GLP-1, GIP, and glucagon for nearly 25% loss. These results are without surgery. Beyond the weight loss, they lower risks for heart disease and diabetes. Of course, new treatments have some challenges. Like making sure they stay safe for long-term use. And managing costs for all the people who need them. But for the first time, we can visualize a future free from the countless physical, emotional, and social burdens caused by obesity. Keep hope alive. A new day is dawning in sustainable medical weight loss care! Appetite Regulation Pathways Obesity treatments that help people lose lots of weight and keep it off target signals to the brain that control hunger and fullness. See, your stomach and gut have cells in them that release different hormones. These “chemical messengers” all serve various functions. They either: Make your brain feel hungry (increase appetite) Make your brain feel full (decrease appetite) Speed up how many calories your body uses (increase energy spending) Some of the major "appetite actors" are: GLP-1 - Helps you feel fuller GIP - Also reduces appetite Glucagon - Energy booster that may curb hunger too Amylin - Blunts appetite and slows digestion PYY - Released to signal you’re full during and after meals GDF-15 Receptor - Growth/differentiation factor 15 (GDF-15) is a stress hormone that seems to play a role in appetite regulation. The hottest new substances for weight loss either turn up the dial on fullness hormones. Or they crank up energy-burning signals. It’s like hacking your body’s appetite remote control! Ozempic, Wegovy, And The Other First Wave of GLP-1 Weight Loss Medications First Generation Medications The first anti-obesity medications to harness appetite hormones paved the way. Specifically, semaglutide under the brand names Ozempic and Wegovy. This injectable drug activates GLP-1 receptor targets. Those signals tell your brain you’re full and can stop eating. In 2021, Wegovy made headlines for helping people lose around 17% of their weight. Far better than anything previously available without surgery! A few other “first-gen” meds include: Liraglutide (Victoza) - Also a GLP-1 agonist injection causing 12% weight loss Danuglipron – Despite high dropout rates, trials saw over 11% reduction Pramlintide (SymlinPen) - An amylin receptor shot leading to around 8% loss Oral semaglutide (Rybelsus) – Ozempic’s cousin in pill form These single hormone meds blazed the trail. But pumping one brake pedal (GLP-1) instead of two or three has its limits. New-era “combination drugs” go further... Combination Therapies - This Is The Future Like assembly lines building cars faster, combination drugs target multiple appetite pathways at once. The more brakes you hit, the more weight comes screeching off! The leader of the pack so far is tirzepatide. This one-two punch activates receptors for both GLP-1 and GIP. Those fullness boosters working together pulled off 16-22% weight loss in studies. Without the risks of surgery. In 2023, it became the first combo med officially approved for obesity with the brand name Zepbound. Others coming down the pipeline take the combo concept even further: Retatrutide: With receptors for GLP-1, GIP, and glucagon all firing at once, phase 3 data shows obese patients losing a jaw-dropping 24% in one year besting even gastric bypass results. Cagrisema: This match made in heaven links GLP-1 and amylin, another hormone lowering food intake and calorie absorption. Early phase 1b data shows the combination resulting in up to 17.1% weight loss. Ongoing phase 3 trials will see if this dynamic duo can maintain results comparable to the best combination therapies. Survodutide: GLP-1 plus glucagon from the tag team sparking trials showing 18% bodyweight reduction. How? Glucagon turns up your energy burner in addition to some appetite effects. Mazdutide: Almost an offshoot of survodutide, this GLP-1/glucagon mixture also torched up to 18% of patients’ pounds in international testing. Pemvidutide: Here GLP-1 joins forces with glucagon as well targeting improved metabolic markers in addition to 15.6% weight loss. Orforglipron: - A yet-to-be-approved daily oral tablet stimulating GLP-1 receptors that's testing up to 14.7% reduction The list keeps marching on with many others recruiting multiple appetitive allies for shielding against weight regain. It’s like hiring more security guards to protect your health! Beyond Gut Hormones Hacking hunger signals and digestion speed are fat-burning gold. But they’re not the only paths to substantial, maintainable weight loss. Other emerging medication classes take different angles attacking obesity’s barriers: Bimagrumab: Instead of suppressing appetite, this IV medication stimulates muscle growth. It blocks activin receptors making the body more efficiently use calories to build lean mass. One trial saw obese diabetics’ fat mass plummet over 20% in just 48 weeks! More muscle means more metabolism boost too. GDF15 Agonists: Want to use obesity's weapons against itself? GDF15 is a hormone produced by fat cells tied to less hunger and food intake. Early evidence shows artificially turning up GDF15 activity with drugs like LY3463251 makes weight slide off. Though larger studies are still needed. Y2 Receptor Agonists: Peptide YY and its effects through Y2 pathways are better researched for cutting appetite. But more testing is underway to develop safe, effective meds targeting these “fullness receptors” in the brain. GPR40 Agonists: Even insulin and blood sugar pathways in the pancreas and gut might have untapped weight loss potential via G protein receptors. Cagrilintide: Rather than a gut hormone, this medication activates amylin receptors involved in appetite signaling. Though not as strong as some multi-agonists, one study still showed almost 10% weight loss at 6 months. Other Compounds That Are In Testing AZD6234 ZP8396 HM15136 NNC0165-1562 Y-14 VK2735 SCO-094 CT-388 Amycretin Dacra QW II NNC0165-1562 and Semaglutide HM15211 NNC0247-0829 JNJ-9090/CIN-109 SCO-267 ZP6590 Conclusion Promise and Challenges Ahead New-era weight loss medications let us envision a future free of obesity’s burdens. But work remains to make the most of their potential. Researchers still need to confirm long-term safety and determine who responds best to which treatments. Other hurdles include: Access & Cost - With loads of combo drugs coming, approval and insurance coverage lags. Out-of-reach costs could stop many from getting life-changing prescriptions. Maintenance - More studies on preventing regain after med-assisted weight loss are important. Can lower doses work? What about periodic re-treatment? Lifestyle Fit - Diet, activity, and behavior changes are still obesity foundations. Where do intensive programs fit alongside meds for ideal results? Safety - These are new drugs and we really don’t know the long-term safety of all of these drugs. So far, they appear to be safe and actually improve health. While questions persist, the progress is still worth celebrating. The obesity struggle is real. But for the first time, sustainable medical weight loss looks achievable for the masses! Melson, E., Ashraf, U., Papamargaritis, D., & Davies, M. J. (2024). What is the pipeline for future medications for obesity? International Journal of Obesity. https://doi.org/10.1038/s41366-024-01473-y This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician or another qualified medical professional. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Tirzepatide Injections Near Me in The Woodlands, TX Everyone is talking about Ozempic, Wegovy, Tirzepatide, Zepbound and Mounjaro. And if you are struggling to lose weight, you may be wondering what is all of the hoopla. Well, have you tried dieting and exercising to lose weight but still can't seem to reach your goals? Haven't we all? But I am going to tell you why Tirzepatide may be the solution you've been looking for. What is Tirzepatide? Tirzepatide is an injectable prescription medication that was originally Federal Drug Administration-approved for treating type 2 diabetes. However, due to its excellent weight loss benefits, it received FDA approval for weight loss in 2023. When it comes to diabetes, it helps lower blood sugar levels by mimicking two natural hormones in your body - glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP). These hormones work together to stimulate the release of insulin when blood sugar is high. However, Tirzepatide has also shown remarkable weight-loss benefits. In clinical trials with people who have obesity or are overweight. Prior to FDA approval for weight loss, healthcare providers were prescribing Tirzepatide "off-label" to help patients struggling with excess weight lower their BMI and improve their health. In fact, in head-to-head testing, Tirzepatide beat out semaglutide (Ozempic) in achieving weight loss. Tirzepatide may be better than semaglutide because it is the only dual gip and glp-1 medication on the market working 2 different ways to balance blood sugars and contribute to weight loss. There are newer dual-action compounds in clinical trials; the future of weight loss will be mind-blowing. How Does Tirzepatide Promote Weight Loss? Tirzepatide promotes weight loss in a few key ways: It slows digestion and causes food to stay in your stomach longer, increasing feelings of fullness so you eat less. It suppresses appetite (cravings) by sending signals to your brain that you are full. It may temporarily alter taste perception or food cravings. It slows the movement of food through your digestive system, further making you feel full longer. While Tirzepatide promotes weight loss through several different pathways, I believe it is the appetite suppression that most weight loss clinics underappreciate. You see, slowing digestion is the cause of most side effects. However, suppressing food cravings will lead to substantial weight loss with minimal side effects. Thus, if you are experiencing side effects, targeting appetite suppression, and cravings, with multiple pathways can reduce side effects, reduce the cost of Tirzepatide treatment, and still achieve significant weight loss. Also, Tirzepatide reduces cravings for alcohol making it a valuable tool for people battling alcohol and other addictions. Tirzepatide Injections for Weight Loss Studies have shown that Tirzepatide can help obese patients lose a significant amount of body weight safely and effectively. Some benefits of Tirzepatide for weight loss include: Average weight loss of 12-22% in clinical trial participants. Reductions in BMI. Decreased abdominal and visceral fat. Improved cardiometabolic health markers like cholesterol and blood pressure. Better ability to manage blood sugar levels. By losing excess weight with Tirzepatide, you can lower your risk for obesity-related conditions like heart disease, fatty liver disease, sleep apnea, osteoarthritis, and type 2 diabetes. Maintaining long-term weight loss also leads to better quality of life. Of course, you may respond to treatment differently and your results may vary. Who is a Candidate for Tirzepatide? Tirzepatide may be an option for adults who: Have a Body mass index of 27 or higher. Struggle with obesity or being overweight. Have weight-related health issues like high blood pressure or high cholesterol. People with food addiction. Overweight people with alcohol use disorder. While anyone can benefit from weight loss, Tirzepatide is specifically helpful for those who have struggled to lose weight by other means. It's important to note that Tirzepatide is only available by prescription. Your health professional will need to determine if Tirzepatide is appropriate for your individual health profile before prescribing it. Certain medical histories or conditions could impact whether Tirzepatide is recommended. What to Expect With Tirzepatide Treatment Tirzepatide is given once weekly via subcutaneous injection - an easy injection you can administer yourself at home. When starting Tirzepatide, your dose will begin low and gradually increase over several weeks. This helps your body adjust and minimizes potential temporary side effects. In clinical trials, mild-to-moderate nausea, vomiting, or diarrhea occurred mainly during the initial dose titration phase. These are typically resolved within a few weeks with no lasting effects. But we can minimize these side effects by targeting appetite suppression with other options. Other possible side effects may include: Decreased appetite Constipation Abdominal pain Rare but serious risks associated with Tirzepatide may also occur. Your health professional will review these with you. While on Tirzepatide, you should follow an individualized weight loss plan tailored to your specific needs. This comprehensive program will develop healthy habits to promote long-term sustained weight loss. Dietary changes Exercise regimen Behavioral strategies Medication Schedule Lifestyle adjustments Goal setting Following this multifaceted plan can help you lose significant weight and sustain results long-term. Sustain Your Tirzepatide Weight Loss Results The key to success with Tirzepatide is combining the medication with healthy lifestyle changes. Diet and exercise remain essential parts of any weight-loss program. Your medical provider will work closely with you to develop maintainable dietary and fitness modifications. With a commitment to the full treatment plan, many people taking Tirzepatide lose substantial weight and report feeling better overall. Find Tirzepatide Injections Near Me If you live near The Woodlands, TX, and want to learn more about using Tirzepatide for weight loss, contact Premier Health & Wellness the Woodlands today at (832) 653-9888. We also cover the whole state of Texas and Oklahoma through our online services. This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician or another qualified medical professional. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Sublocade Injections Near Me in The Woodlands, TX Quiet places like The Woodlands in Montgomery County are facing a big problem. It's called the opioid crisis. This involves heroin, fentanyl, nitazenes, kratom, tianeptine, and so many other street drugs leading to overdose deaths. Frequently, individuals who have undergone surgery, experienced pain, or suffered trauma are prescribed strong pain medications, such as hydrocodone, morphine, hydromorphone or oxycodone. But this can quickly turn into a dangerous habit that's hard to break. Our friends, neighbors, and family members, might then start using street drugs. Getting high is no longer the goal. Addicts find themselves taking opioids just to prevent the opioid withdrawals.. This problem, called Opioid Use Disorder (OUD), is not just a medical issue; it changes people's lives in sad and serious ways, influencing not just the person but their whole family as well. The good news is that we offer innovative medication-assisted treatments (MAT) that can help opioid addicts regain control. One of the most exciting new options is Sublocade - a newer buprenorphine injection that continues to work for the whole month after a single injection. Keep reading to learn how Sublocade works and why it presents such a great improvement as part of a treatment program.. A Closer Look at Opioid Use Disorder Prescription opioid pain relievers and illicit opioids hijack the brain's natural reward system. With continued exposure, progressively more and more opioids are needed to achieve the same high or same pain relief. Over time, the compulsion to use opioids can overshadows everything else in an addict's life. Jobs, relationships, health, responsibilities are no longer as important as avoiding the agonizing pain of opioid withdrawal. Opioid addiction is not a moral failing or lack of willpower. It literally changes brain structure and function. The condition meets established medical criteria as a chronic relapsing disease. Without proper treatment, OUD has grim prospects. But the medication buprenorphine has given hope to many addicts through its ability to manage withdrawal symptoms, curb cravings and prevent overdose deaths. Sublocade builds on buprenorphine's strengths by freeing patients from the need to take medication daily. This groundbreaking shift can remove obstacles to recovery and helps prevent misuse of medication. What Exactly is Sublocade? Manufactured by Indivior, the same maker of Suboxone, Sublocade contains buprenorphine, the same active ingredient found in Suboxone. Like any other form of buprenorphine used to treat opioid use disorder, Sublocade treats cravings and withdrawal symptoms. As part of an addiction treatment program, addicts can focus on their responsibilities, their families, and stop taking opioids. However, Sublocade has a key difference by using a specialized delivery system to provide sustained-release buprenorphine over the course of one month. After one subcutaneous injection by a Sublocade doctor, the medication forms a solid deposit which slowly dissolves. Therapeutic buprenorphine blood plasma levels persist for the entire month before starting to taper during the fourth week. Sublocade eliminates the daily medication dosing that oral buprenorphine requires. The once-monthly injections also produce more stable blood levels without peaks and troughs. Patients avoid GI tract absorption issues, dental issues, and experience fewer side effects like headaches or nausea. The embedded taper effect provides a cushion as the next month's injection approaches. At Premier Health & Wellness The Woodlands, we are finding that Sublocade assists in tapering off of buprenorphine better than the oral form. Thus, we have designed a protocol to help people taper completely off of buprenorphine in a much quicker timeframe. All of these advantages give Sublocade users their best shot at compliance and long-term success beating opioid addiction. How Sublocade Treatment Works The recommended dosing regimen starts with two monthly 300 mg injections, followed by 100 mg monthly maintenance doses. After the loading doses reach steady therapeutic levels, most patients only need one brief monthly appointment. That makes keeping up with treatment so much easier long-term. The injection process only takes about 5-10 minutes. The site is cleaned and a local anesthetic administered before the thin needle is inserted subcutaneously into the abdominal area. There is some burning during injection and occasional residual soreness. But overall Sublocade injections are well-tolerated. The only facility requirements are basic refrigeration and a locked storage space. Once at room temperature, Sublocade can be administered straight from the shipping container. And self-injection abuse and diversion risks are eliminated by administration under medical supervision. Sublocade's Advantages Over Other Treatment Options Daily oral buprenorphine, such as Subutex and Suboxone, is a well-established treatment for OUD. So why choose a new delivery method? Sublocade offers compelling advantages: Fewer Side Effects - Avoiding medication ups & downs minimizes side effects. Discreet - No need for carrying medications or remembering daily doses. Prevents Diversion - Supervised monthly administration prevents misuse. Simplifies Compliance - Only monthly visits instead of daily dosing. Gradual Taper - Slow dissipation avoids precipitated withdrawal. Polysubstance abuse is common with opioid addiction. Many OUD sufferers also battle alcohol, benzodiazepine and stimulant addictions in their efforts to manage their opioid withdrawals. Sublocade helps stay focused on recovery instead of opioid cravings or withdrawal symptoms. For people struggling through multiple previous relapse cycles, Sublocade may offer a needed fresh start. The injection's set-it-and-forget-it approach better suits real-world conditions. Finally, Sublocade gives family members peace of mind. Loved ones often safeguard medications or administer daily doses for addicted relatives. With supervised monthly injections, the grind of addiction oversight is lifted, and relationships begin healing. Sublocade Cost and Availability in The Woodlands, Texas The only pharmacological treatments proven effective for OUD are buprenorphine, methadone, and extended-release naltrexone. Thankfully, the vast majority of private health plans cover these medication-assisted treatment options. Most patients pay a typical visit fee for the monthly Sublocade injection and monitoring appointment. For patients without insurance, the monthly cost of Sublocade is high and averages around $1500. However, most addicts admit that this is considerably less than the cost of their addiction. We work with you to obtain discounts from the manufacturer. Texans have access to plenty of Sublocade providers across the state and nearby by in Houston. However, we want Premier Health & Wellness The Woodlands to be your choice for life-changing Sublocade treatment in The Woodlands area. We handle the insurance authorization process and provide integrated therapy for the best possible odds of long-term recovery success. Sublocade FAQs How long does each Sublocade injection last? Steady therapeutic buprenorphine levels persist for around 28 days from each dose. After the first two loading doses, subsequent monthly maintenance injections continue providing effective treatment. Does the injection site matter? Sublocade is only administered subcutaneously in the abdominal area using a small gauge needle into fatty tissue beneath the skin. Injection sites alternate monthly between left and right sides. When does the tapering effects begin? The taper effect starts during the 4th week as the embedded buprenorphine matrix begins dissolving. The gradual decrease helps avoid withdrawal symptoms before the next monthly injection. What happens after finishing Sublocade treatment? It takes around 6 to 12 months for remaining buprenorphine to fully metabolize and excrete after the last injection. Medical teams carefully plan transition, using clonidine, naltrexone, non-opioids, and psychotherapy to prevent relapse. How long should treatment last? Clinical trials demonstrate Sublocade’s safety and efficacy for up to 12 months. But as a chronic relapsing condition, many patients benefit from continued MAT to sustain recovery. The length depends on the patient’s needs and preferences. Break the Chains of Opioid Addiction Once and For All With the advent of innovative medical options like Sublocade, freedom from the chains of opioid addiction is closer than ever. The compulsion to use can relent. Cravings can fade. Clear eyes and clear minds prevail. Serenity fills days previously consumed by desperation. Help is here. To learn more about how Sublocade treatment offered through Premier Health & Wellness The Woodlands, request a consultation today. Call (832) 653-9888 now to get started. This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician or another qualified medical professional. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Brixadi Near Me Opioid use disorder (OUD) is a growing epidemic in the United States. Overdose deaths from prescription and illicit opioids have skyrocketed in recent years. But it's not just a problem in the US or Houston, it is in The Woodlands, Texas too. Remember the 2 high school overdose deaths in 2022? The problem is real and it's all around us. Opioid use disorder is a real disease and not a problem of morality. People with this disorder go from enjoying euphoria (high) to a life filled with constant cravings and withdrawal symptoms. These withdrawal symptoms are painful. Within several weeks of using opioids, people become hooked and eventually stop experiencing the high. Instead, they become enslaved to using opioids just to avoid the painful withdrawals. When they can't get prescription opioids, they turn to friends, family, and drug dealers for drugs. These illicit drugs can be laced with heroin, fentanyl, tianeptine, nitazenes, kratom, and xylazine placing users at high risk for overdose death. Fortunately, new medications like Brixadi and Sublocade provide healthcare professionals with more tools to treat this complex disorder. This post will cover everything you need to know about using Brixadi to treat opioid dependence. What is Brixadi? Brixadi is the brand name for a buprenorphine extended-release injection used to treat opioid use disorder. It received Food and Drug Administration (FDA) approval in 2023. That is very new but using buprenorphine to treat opioid addiction is decades old. Brixadi treatment is available in both weekly and monthly doses. The weekly injections contain dosages of 8 mg, 16 mg, 24 mg, or 32 mg of buprenorphine. The monthly doses contain 64 mg, 96 mg, or 128 mg. The injection is given underneath the skin of the buttock, thigh, or abdomen. There, it slowly dissolves into the bloodstream. , How Does Brixadi Treat Opioid Addiction? Brixadi belongs to a class of medications called partial opioid agonists. It activates the same opioid receptors in the brain that other opioids like heroin or prescription pain pills do. However, it activates these receptors less strongly than full agonists. So, no high occurs and no loss of control occurs. This helps reduce opioid cravings and withdrawal symptoms. At the same time, it has a “ceiling effect” so higher doses don’t produce euphoric highs and won't depress your ability to breathe. When combined with counseling, partial agonists like Brixadi facilitate opioid detox and long-term recovery. What Are the Benefits of Brixadi Injections? Brixadi offers a valuable new tool for medication-assisted treatment (MAT) of opioid use disorder. Here are some key benefits: Extended-release formula. The Brixadi subcutaneous injection slowly releases buprenorphine over 1 week to 1 month depending on the dose. So patients don’t have to take it daily. This improves compliance. Fewer peaks and troughs. Levels of buprenorphine stay steadier compared to oral tablets and films that fluctuate widely. This minimizes side effects. Harder to misuse. The injection formulation almost eliminates diversion, misuse, and abuse risks that exist with daily sublingual films or tablets. Better treatment outcomes. Clinical trials found that Brixadi matched or outperformed conventional oral buprenorphine. For example, it produced higher rates of opioid-free urine drug tests. What Are Possible Side Effects of Brixadi? The most common side effects of Brixadi are: Injection site reactions (e.g. pain, itching, redness) Headaches Nausea Insomnia Constipation More serious side effects may include: Respiratory depression Neonatal opioid withdrawal (if used during pregnancy) Adrenal insufficiency Patients with liver problems should use caution when using Brixadi. What is the Brixadi REMS Program? Due to the risks of IV misuse, the FDA requires Brixadi to be dispensed through a restricted program called a Risk Evaluation and Mitigation Strategy (REMS). Under this program: Healthcare providers must be REMS certified to store supplies of Brixadi Pharmacies must be certified to order and dispense Brixadi Providers cannot transfer Brixadi to patients directly The goal is to reduce harm by ensuring proper administration and monitoring. Who is a Good Candidate for Brixadi? Patients with opioid use disorder who: Have tried medication-assisted treatment before. Struggle with compliance using daily buprenorphine. Misuse or divert buprenorphine tablets/films. Want an opioid detox and maintenance plan that fits their lifestyle. Talk to us at (832) 653-9888 and see if Brixadi is right for your OUD recovery needs. How is the First Brixadi Dose Administered? If new to treatment, patients should take at least one dose of oral buprenorphine first to make sure they tolerate buprenorphine. If currently using transmucosal buprenorphine, patients can switch directly to Brixadi without needing an oral test dose. The first injection is usually 16 mg. A healthcare provider may give an extra 8 mg within 3 days if needed. Subsequent weekly or monthly doses get tailored to the patient’s needs. Where Can I Find Brixadi Near Me? Since the Brixadi REMS program strictly controls its distribution, you may wonder - where can I find a medical professional to prescribe Brixadi near me? The best approach is to schedule a consultation with one of our addiction medicine experts at Premier Health & Wellness The Woodlands. We serve the greater Houston metro area. Our clinical team can determine if Brixadi or another option is appropriate for your situation. Don't continue struggling with opioid dependence alone. Call us today at (832) 653-9888 to ask any and all questions about Brixadi for OUD treatment or to set up an appointment. We offer comprehensive support to help you achieve sobriety one step at a time. This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician or another qualified medical professional. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Semaglutide Near Me You are not the only one having difficulty fighting obesity or battling excess weight alongside health issues such as type 2 diabetes or hypertension. As with anyone else, trying to lose weight might feel overwhelming. But a major revolution is occurring that most people still don't know about. In 2021, the Food and Drug Administration (FDA) approved the drug Wegovy (Semaglutide) for long-term weight management, and it's now available to you. This medication could be a game-changer in your weight loss adventure, especially when paired with positive lifestyle modifications. What Exactly is Semaglutide? Semaglutide works in several ways. First, semaglutide stimulates glucagon-like peptide-1 (GLP-1) receptors in the brain that control appetite and food intake. It eliminates cravings. You may not feel hungry for hours longer than usual. You might have to remind yourself to eat. The second-way semaglutide injections work is by slowing down the movement of food through your digestive system. In a similar fashion to your natural hormone, semaglutide reduces appetite and causes feelings of fullness, leading to reduced eating and weight loss. This causes less snacking in between meals. The third way semaglutide works is by helping to control blood sugar levels, which also benefits weight loss. Remember, Ozempic (semaglutide) was originally approved by the Food and Drug Administration to manage diabetes. It was later approved by the FDA for weight loss under the trade name Wegovy. Now, a compounded form of semaglutide is available specifically for chronic weight management and not just diabetes. This makes its weight loss effects accessible to more people struggling with obesity. Who Can Benefit from Semaglutide? Most health insurance companies will provide coverage for semaglutide based upon the FDA-approved indications. Adults struggling with obesity or who are overweight with at least one weight-related health condition. Such conditions include: Type 2 diabetes High blood pressure High cholesterol Obstructive sleep apnea Certain types of heart disease So if you have a BMI of 30 or higher or a BMI of 27+ with a weight-related condition, semaglutide may be approved by insurance and help you achieve significant weight reduction for better health. Expected Weight Loss Results In clinical trials, semaglutide has been shown to deliver considerable weight loss results over time. The average total body weight loss seen in studies was 16.7% over nearly two years of continued treatment. Of course, results may vary from person to person. Over the first 16 to 20 weeks specifically, trials showed most people lose around 5-10% of their starting body weight. Then, weight loss tends to plateau somewhat but additional smaller reductions may occur with steady use. For someone weighing 200 pounds initially, this could mean losing up to around 20 pounds in the first several months! So while semaglutide is not a quick fix, it can support healthy, sustainable long-term weight management when combined with lifestyle changes. Is Semaglutide Right For Me? If you're struggling to lose weight or keep it off through diet and exercise alone, semaglutide may help. It is meant to be used along with a weight loss plan involving regular physical activity and nutritious low-calorie eating. Give us a call to find out if semaglutide is appropriate for your unique health situation. A customized treatment plan can then be created to help you achieve your goals. Let's evaluate your: Weight and BMI Medical history Current medications Lifestyle and eating habits Motivation for weight loss Prior attempts at losing weight Any food addictions This information helps determine if semaglutide fits into your overall plan of care. It also establishes reasonable expectations about the amount and time frame of weight reduction possible for your circumstances. What to Expect When Starting Semaglutide Semaglutide is given via simple injection under the skin once weekly. The injection site can be changed each time to different areas like your thigh or abdomen. When beginning semaglutide, the dose starts low and then slowly increases over time to improve tolerance of side effects. Common temporary side effects can include nausea, vomiting, diarrhea, and loss of appetite. These typically resolve within days to weeks as your body adjusts. Throughout treatment, you will have regular check-ins with your medical provider to monitor weight loss progress and manage any medication side effects. Bloodwork and other testing may be ordered to ensure Semaglutide's effects on things like blood sugar are on track. The typical duration of semaglutide for weight management is at least 16 weeks. Often though, it is continued beyond this point if still helping facilitate weight reduction and better health. The Weight Loss Journey Continues Losing weight is rarely quick or easy, but the payoff for health is immense. Semaglutide injections for weight loss used appropriately can be a powerful tool when combined with healthy lifestyle changes. It may just help you achieve weight loss success when other attempts have failed. But remember, semaglutide is not magic. It works best as one piece of an overall plan of care supervised by a medical provider. Working together, an effective path forward can be mapped out. If you believe you may benefit from semaglutide for chronic weight issues, take the next step. Contact us today to ask about treatment options. This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician or another qualified medical professional. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

What to Expect When You Start Hormone Replacement Therapy You've completed your first appointment with me and now you are about to start treatment. Starting hormone replacement therapy (HRT) can provide welcome relief for unpleasant menopause symptoms. But there may be lingering questions after leaving your first appointment. The goal of this post is to give you realistic information on what to expect, both benefits and side effects, while you pursue HRT. We’ll cover: How hormone therapy works Expected timeline for symptom relief Possible short-term side effects Long-term health benefits Risks to be aware of Tips to get the most out of treatment Let’s get started! How Hormone Replacement Therapy Works HRT involves taking small doses of hormones like estrogen, progesterone, testosterone, DHEA, and others to restore normal levels. This relieves symptoms that occur from the declines during menopause. The most common delivery methods are: Estrogen and progesterone pills Skin patches Vaginal rings Gels or creams Pellets placed under the skin Bioidentical hormones have the same chemical structure as your body’s hormones. They are engineered to be identical matches and bind optimally to hormone receptors. The right combination and dosing will balance your hormones for optimal functioning. Let’s see what you can expect in the first weeks and months after starting HRT. What to Expect in the First Months Most women notice some effects within 1-2 weeks after beginning hormone therapy. But the full benefits build gradually over 3-6 months as levels regulate. Here's a look at the timeline you can expect: 1-2 Weeks Increased energy Improved mood and sleep Some relief from hot flashes/night sweats 1 Month More stable moods Fewer sleep disruptions Less vaginal dryness during sex Some hot flashes subsided 2-3 Months Significant reduction in hot flashes Less stiffness and joint pain Increased muscle tone Improved skin texture and moisture Thicker, shinier hair Better sleep quality 3-6 Months Resolution of sleep problems Balanced mood - less irritability Clearer thinking and focus Reversal of weight gain Restored libido and sexual satisfaction An overall sense of wellbeing While benefits accumulate over months, most women report feeling dramatically better within 6-8 weeks. What About Side Effects? Some women experience temporary side effects when first starting HRT while the body adjusts: Breast tenderness or swelling Headaches Nausea Bloating Redness/irritation at patch application sites These symptoms usually resolve within 2-3 months. But let me know if they persist. There is also a small risk of blood clots in the first year for some women taking oral estrogen. So be aware of any leg pain, redness, or swelling and report it promptly. Otherwise, most women adjust without problems and enjoy the many benefits that make them feel like themselves again. , Long-term Effects: Weighing Benefits Research shows hormone therapy has significant benefits when taken for up to 5-7 years: Benefits: Alleviates menopause symptoms Reduces bone loss and risk of osteoporosis Lowers LDL cholesterol Protects metabolic health - improves insulin sensitivity Reduces risk factors for heart disease Preserves cognitive function and lowers dementia risk Protects collagen and skin health Maintains fitness, muscle strength, and endurance Tips to Get the Most Out of HRT Here are some suggestions to follow that will help you get optimal results: Take hormones regularly - Try to stick to consistent times and never skip more than 1-2 days. Don’t stop abruptly - Taper down dosage over several weeks when ending therapy to prevent symptoms from rebounding. Use the lowest effective dose - I will adjust to meet your needs while minimizing risks. Get follow-up blood tests: Monitoring your levels helps determine ideal dosing. So, please don't miss our appointments. Report any side effects - Promptly notify me about any unusual symptoms. Implement a healthy lifestyle - Nutritious eating, regular exercise, stress management, and good sleep hygiene will all enhance results. Get your screenings - Have regular mammograms, lipid profiles, bone density tests, pelvic exams, etc. to monitor your health on HRT. Consider adding testosterone: Testosterone therapy provides additional benefits for some women. We can discuss testosterone if I haven't already done so. Take the Next Step for Your Improvement Understanding what to expect will help you get started on the path to feeling your best again. Now that you have realistic information about hormone therapy, you can start your journey and have peace of mind about what’s ahead. I hope this post helped you learn what to expect when starting hormone replacement therapy during symptoms of menopause. Don't hesitate to reach out with any other questions! I'm here to help support your hormone health and vitality. This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician or another qualified medical professional. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.